All the children of the Prophet (peace and blessings of Allah be upon him) were from Sayyeda Khadija except Ibrahim who was born to Maria the Coptic, the first of the children of the Prophet (peace and blessings of Allah be upon him) was Al-Qasim (which was why he was nicknamed Abu Al-Qasim ), then they had Zainab, Ruqaia, um Kulthum, Fatima and Abdullah, and Abdullah was nicknamed the Tahir. His sons all died when they were young, while all the daughters lived to witness Islam and they embraced it and emigrated, but they all died during the life of the Prophet (peace and blessings of Allah be upon him), except Fatima, may Allah be pleased with her, who died six months after his death.
كل اولاد الرسول صلى الله عليه وسلم من السيدة خديجة ماعدا ابراهيم من ماريا القبطية، اول اولاد الرسول صلى الله عليه وسلم: القاسم وبه كان يكنى، ثم زينب ورقية ، وأم كلثوم وفاطمة وعبد الله، وكان عبد الله يلقب بالطاهر الطيب. ومات بنوه كلهم في صغرهم ، أما البنات فكلهن أدركن الإسلام فأسلمن وهاجرن، إلا أنهن ادركتهن الوفاة في حياة الرسول صلى الله عليه وسلم، سوى فاطمة رضي الله عنها لحقت به بعد موته بستة أشهر.